abstract：:Infection can be a trigger and an aggravating factor in psoriasis. Antibacterial and/or antifungal agents are commonly used in the treatment of intertriginous psoriasis, because it is believed that flexures in psoriasis are often colonized by Candida species and Staphylococcus aureus. Bacterial and fungal cultures wer...

journal_title：Acta dermato-venereologica

authors： Flytström I,Bergbrant IM,Bråred J,Brandberg LL

更新日期：2003-01-01 00:00:00

abstract：:To evaluate plasma lipid peroxidation and enzymatic and non-enzymatic antioxidant systems in patients with Behçet's disease, plasma malondialdehyde levels and total antioxidant status, erythrocyte superoxide dismutase and whole blood glutathione peroxidase activities were studied in 15 patients with active disease and...

journal_title：Acta dermato-venereologica

authors： Sandikci R,Türkmen S,Güvenen G,Ayabakan H,Gülcan P,Koldas M,Ozbek Kir Z,Yenice N

更新日期：2003-01-01 00:00:00

abstract：:Given the long purported anecdotal association between rosacea and gastrointestinal disease, the discovery that Helicobacter pylori causes gastritis and duodenal ulcer disease has led to a hypothesized role for this organism in the aetiology of rosacea. We conducted a case-series study of 49 patients to assess the pot...

journal_title：Acta dermato-venereologica

authors： Diaz C,O'Callaghan CJ,Khan A,Ilchyshyn A

更新日期：2003-01-01 00:00:00

abstract：:We present a 32-year-old white patient with congenital reticular ichthyosiform erythroderma, also known as ichthyosis variegata. The patient had typical clinical features with areas of normal appearing skin surrounded by erythematous hyperkeratotic patches. The smaller "confetti-like" patches were mostly present on th...

journal_title：Acta dermato-venereologica

authors： Krunic AL,Palcesky D,Busbey S,Medenica M

更新日期：2003-01-01 00:00:00

abstract：:Glycosaminoglycans are important components of all extracellular matrices. One of the glycosaminoglycans is hyaluronan, which is ubiquitously distributed throughout the connective tissue. Hyaluronan is especially abundant in the skin, in which it is of both structural and functional importance. This study describes th...

journal_title：Acta dermato-venereologica

authors： Bertheim U,Engström-Laurent A,Hofer PA,Hallgren P,Asplund J,Hellström S

更新日期：2002-01-01 00:00:00

abstract：:Experience gained from cooperation between dermatologists and vascular surgeons in 177 patients evaluated at a joint leg ulcer clinic is reported. Patients were divided into two subgroups: (i) 86 patients with healed ulcers and (ii) 91 patients with ongoing therapy-resistant ulcers. Venous insufficiency was the most c...

journal_title：Acta dermato-venereologica

authors： Bjellerup M,Akesson H

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to investigate the suitability and effectiveness of heliotherapy in moderate or severe atopic dermatitis in adults in the Canary Islands. A total of 216 patients participated on 6 different 2- or 3-week heliotherapy trips. Using the Severity Scoring of Atopic Dermatitis Index (SCORAD), the se...

journal_title：Acta dermato-venereologica

authors： Autio P,Komulainen P,Larni HM

更新日期：2002-01-01 00:00:00

abstract：:In this article, the results of 3 studies on 2 hand cleansers (products A and B) are analysed. Three different test models (the patch test, the forearm wash test and the use test) are used to obtain information on the skin irritancy of these 2 products. Test reactivity was assessed by clinical scores and bioengineerin...

journal_title：Acta dermato-venereologica

authors： Spoo J,Wigger-Alberti W,Berndt U,Fischer T,Elsner P

更新日期：2002-01-01 00:00:00

abstract：:We present a young male patient referred to our hospital with leg ulcers on both legs that were more than 3 years refractory to standard treatment with compression therapy. By thrombophilia screening factor V Leiden mutation, hyperhomocysteinemia and evidence for impaired fibrinolysis were found. Treatment with folic ...

journal_title：Acta dermato-venereologica

authors： Kolbach DN,Veraart JC,Hamulyák K,Spaapen LJ,Neumann HA

更新日期：2002-01-01 00:00:00

abstract：:Although palmoplantar psoriasis can be severely disabling, there are very few large clinico-epidemiological studies on this condition. Our purpose was to study the morphology and pattern of lesions in Indian patients with palmoplantar psoriasis and to elucidate the role of occupation in the incidence/localization of t...

journal_title：Acta dermato-venereologica

authors： Kumar B,Saraswat A,Kaur I

更新日期：2002-01-01 00:00:00

abstract：:Anisakis simplex is a seafish nematode, which is responsible for the well-known human infection (anisakiasis) and can induce IgE-mediated reactions. IgE sensitization to Anisakis simplex can be frequent in particular countries and should be suspected in patients with acute allergic symptoms after ingestion of fish. Th...

journal_title：Acta dermato-venereologica

authors： Foti C,Nettis E,Cassano N,Di Mundo I,Vena GA

更新日期：2002-01-01 00:00:00

abstract：:The effect of a protective cream was tested in a new tandem repeated irritation test with tandem application of 0.5% sodium lauryl sulphate (SLS) and undiluted toluene. The irritants were applied twice daily for 30 min to the ventral forearms of 20 volunteers. Irritant cutaneous reactions were quantified by a visual s...

journal_title：Acta dermato-venereologica

authors： Wigger-Alberti W,Spoo J,Schliemann-Willers S,Klotz A,Elsner P

更新日期：2002-01-01 00:00:00

abstract：:The aim of the study was to investigate the effect of non-allergenic structural analogues on the sensitizing potential of carvone, a fragrance allergen. The possibility that one molecule might inhibit the allergenic activity of another molecule has been debated for 25 years. The Research Institute for Fragrance Materi...

journal_title：Acta dermato-venereologica

authors： Karlberg AT,Nilsson AM,Luthman K,Nilsson JL

更新日期：2001-11-01 00:00:00

abstract：:Atopic dermatitis is a multifactorial disorder probably caused by environmental factors in combination with susceptibility genes. The clinical similarity between atopic dermatitis and the eczema manifestation in patients with Wiskott-Aldrich syndrome made the previously identified WAS gene in chromosome sub-band Xpl 1...

journal_title：Acta dermato-venereologica

authors： Bradley M,Söderhäll C,Wahlgren CF,Luthman H,Nordenskjöld M,Kockum I

更新日期：2001-10-01 00:00:00

abstract：:Eight substances (histamine, compound 48/80, kallikrein, trypsin, papain, substance P, serotonin and platelet activating factor) were injected intradermally (volume 50 microl) into the rostral back (neck) of rats in order to establish an animal model for peripherally elicited pruritus. While serotonin induced excessiv...

journal_title：Acta dermato-venereologica

authors： Thomsen JS,Petersen MB,Benfeldt E,Jensen SB,Serup J

更新日期：2001-08-01 00:00:00

abstract：:Mesotherapy is a treatment method devised for controlling pain syndromes or diseases by subcutaneous microinjections given at or around the involved areas at short intervals of time. Different adverse effects have been described due to this modality of treatment. This report describes 3 patients with cutaneous infecti...

journal_title：Acta dermato-venereologica

authors： Nagore E,Ramos P,Botella-Estrada R,Ramos-Níguez JA,Sanmartín O,Castejón P

更新日期：2001-08-01 00:00:00

abstract：:A trioxysalen bath is a safe alternative to systemic 8-methoxypsoralen in long-term psoralen plus ultraviolet A (PUVA) treatment. The kinetics of its main side-effect, the strong phototoxicity, has not been thoroughly studied. This study determined the degree and persistence of phototoxicity after a single 10 min bath...

journal_title：Acta dermato-venereologica

authors： Snellman E,Rantanen T

更新日期：2001-06-01 00:00:00

abstract：:Conflicting results regarding the association of a polymorphism at codon 72 of the p53 tumour suppressor gene and susceptibility to develop human papilloma virus (HPV)-associated cervical cancer have been published over the last year, implicating differences in ethnic background, sample origin, sample size and/or dete...

journal_title：Acta dermato-venereologica

authors： Gustafsson AC,Guo Z,Hu X,Ahmadian A,Brodin B,Nilsson A,Pontén J,Pontén F,Lundeberg J

更新日期：2001-05-01 00:00:00

abstract：:We analysed the cytokine profile of skin T cells by establishing 11 T-cell lines from adult patients with moderate-to-severe atopic eczema using T-cell growth factors interleukin-2 and interleukin-4. We compared T-cell lines from lesional skin of atopic dermatitis patients with those from non-atopic skin of patients w...

journal_title：Acta dermato-venereologica

authors： Higashi N,Bang K,Gesser B,Lund M,Thestrup-Pedersen K

更新日期：2001-01-01 00:00:00

abstract：:Psoriasis is probably a T-cell-mediated autoimmune disease. Infectious models of autoimmune diseases have been proposed and in psoriasis, it has been suggested that there may be molecular mimicry between streptococcal antigens and epidermal keratins. The immunological profile of stable psoriasis plaques suggests, howe...

journal_title：Acta dermato-venereologica

authors： Kirby B,Al-Jiffri O,Cooper RJ,Corbitt G,Klapper PE,Griffiths CE

更新日期：2000-11-01 00:00:00

abstract：:Some confusion exists in the literature about which criteria should be used to define familial melanoma. This could explain the different reported frequencies of mutations in predisposing genes, mostly CDKN2A, in these patients. This study evaluated the human leucocyte antigen (HLA) class II genotype and the presence ...

journal_title：Acta dermato-venereologica

authors： Nagore E,Climent J,Planelles MD,Ledesma E,Rubio-Moscardó F,Fortea JM,Oliver V

更新日期：2000-11-01 00:00:00

abstract：:EMLA cream, which is used to provide analgesia prior to venepuncture, induces a skin-blanching reaction. This reaction may be caused by both skin hydration and vasoconstriction. Twenty healthy children with veins suitable for venepuncture on the dorsa of the hands or at the antecubital fossae had applied either EMLA c...

journal_title：Acta dermato-venereologica

authors： Egekvist H,Bjerring P

更新日期：2000-09-01 00:00:00

abstract：:Actinomycotic mycetomas usually respond slowly to treatment with antibiotics. In an attempt to hasten clinical resolution, we used a 2-step regimen consisting of an intensive phase of therapy with penicillin, gentamycin and co-trimoxazole for 5-7 weeks, followed by maintenance therapy with amoxicillin and co-trimoxazo...

journal_title：Acta dermato-venereologica

authors： Ramam M,Garg T,D'Souza P,Verma KK,Khaitan BK,Singh MK,Banerjee U

更新日期：2000-09-01 00:00:00

abstract：:The aim of the present study was to provide data on the reliability and validity of a Danish translation of the Dermatology Life Quality Index (DLQI), a short measure of the impact of dermatological diseases on quality of life. The DLQI was administered to 200 outpatients and 100 hospitalized patients suffering from a...

journal_title：Acta dermato-venereologica

authors： Zachariae R,Zachariae C,Ibsen H,Mortensen JT,Wulf HC

更新日期：2000-07-01 00:00:00

abstract：:Data on skin reactivity in patients with respiratory atopy without atopic dermatitis are scarce and controversial. Our purpose was to assess whether skin reactivity in patients with seasonal allergic rhinitis varies according to the phase of the disease and the possible release of inflammatory mediators acting on the ...

journal_title：Acta dermato-venereologica

authors： Conti A,Seidenari S

更新日期：2000-05-01 00:00:00

abstract：:In order to study the flare-up of contact allergy, 35 patients with a contact allergy to gold were given an intramuscular injection of 10 mg gold sodium thiomalate, i.e. the anti-rheumatic drug Myocrisin. Clinical reactions comprised an eczematous flare-up of previously positive patch tests to gold and of a previous d...

journal_title：Acta dermato-venereologica

authors： Möller H

更新日期：2000-03-01 00:00:00

abstract：:Air-borne contact dermatitis caused by Parthenium hysterophorus is a serious problem in India. Patients with this condition have to use corticosteroids regularly in order to maintain clinical remissions, but prolonged usage causes serious side-effects. The weed cannot be eradicated. We have used 3 therapeutic regimens...

journal_title：Acta dermato-venereologica

authors： Verma KK,Manchanda Y,Pasricha JS

更新日期：2000-01-01 00:00:00

abstract：:Previous investigations have indicated that topical azelaic acid has beneficial effects in rosacea. This 3-month randomized, double-blind, multicentre study compared the efficacy and safety of azelaic acid 20% cream with its vehicle, in the treatment of papulo-pustular rosacea. A total of 116 patients were enrolled in...

journal_title：Acta dermato-venereologica

authors： Bjerke R,Fyrand O,Graupe K

更新日期：1999-11-01 00:00:00

abstract：:Different scoring systems have been developed to determine the severity of atopic dermatitis. The SCORAD (SCORing Atopic Dermatitis), one of the best validated systems, is suited for clinical trials, but is too complicated and time consuming for routine clinical use. The TIS score (Three Item Severity score), a simpli...

journal_title：Acta dermato-venereologica

authors： Wolkerstorfer A,de Waard van der Spek FB,Glazenburg EJ,Mulder PG,Oranje AP

更新日期：1999-09-01 00:00:00

abstract：:The anti-inflammatory mechanisms of minocycline, an antibiotic used in the treatment of the inflammatory component of acne, are only partially understood. In addition to inflammation due to cytokines (IL-1, IL-6, TNF-alpha, etc.), recent studies have shown that neuropeptide-mediated neurogenic inflammation may play an...

journal_title：Acta dermato-venereologica

authors： Sainte-Marie I,Tenaud I,Jumbou O,Dréno B

更新日期：1999-07-01 00:00:00

abstract：:Hypopigmented macules are frequently observed in the photodamaged skin of elderly people. We undertook to study and treat 2 types of hypomelanosis of photoaged skin. These lesions were: 1) idiopathic guttate hypomelanosis; and 2) macular hypomelanosis. Comparative studies included: 1) high-resolution photography using...

journal_title：Acta dermato-venereologica

authors： Pagnoni A,Kligman AM,Sadiq I,Stoudemayer T

更新日期：1999-07-01 00:00:00

abstract：:We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the di...

journal_title：Acta dermato-venereologica

authors： Kim IH,Jo HY,Cho CG,Choi HC,Oh CH

更新日期：1999-05-01 00:00:00

abstract：:To investigate the function of trichohyalin during terminal differentiation of the skin, immunohistochemical studies were performed on trichohyalin and its related proteins, filaggrin and involucrin, the components of the cornified cell envelope. In skin disorders unrelated to tumours, weak trichohyalin expression was...

journal_title：Acta dermato-venereologica

authors： Lee SC,Lee JB,Seo JJ,Kim YP

更新日期：1999-03-01 00:00:00

abstract：:In an attempt to clarify the pathophysiology of haemodynamics in legs with venous ulcer we investigated the effect of a single intermittent pneumatic compression treatment on the peripheral resistance of leg arteries and the cutaneous laser Doppler flux in the leg. Eight patients with venous leg ulcers and 10 subjects...

journal_title：Acta dermato-venereologica

authors： Malanin K,Kolari PJ,Havu VK

更新日期：1999-03-01 00:00:00

abstract：:Intraepidermal collections of neutrophils and lymphocytes are unique features of the inflammatory reaction of psoriasis. Migration of leukocytes from dermis to the epidermis suggests a role for chemotactic agent(s). In recent years, increased levels of chemokines such as IL-8 , GRO-a and MCP-1 have been reported in th...

journal_title：Acta dermato-venereologica

authors： Raychaudhuri SP,Jiang WY,Farber EM,Schall TJ,Ruff MR,Pert CB

更新日期：1999-01-01 00:00:00

abstract：:Three patients with onychomycosis due to Trichophyton soudanense with an "endonyx" type of nail invasion are presented. Endonyx onychomycosis is clinically characterized by a diffuse milky-white discolouration of the affected nail, in the absence of nail bed hyperkeratosis or onycholysis. Nail plate surface and nail t...

journal_title：Acta dermato-venereologica

authors： Tosti A,Baran R,Piraccini BM,Fanti PA

更新日期：1999-01-01 00:00:00

abstract：:Previous studies have shown that magnetic resonance imaging is more sensitive in assessing soft tissue and bone involvement in inflammatory arthritis than conventional radiography. Therefore the main objects of this study were to evaluate the frequency of hand involvement in psoriatic patients free from arthritic symp...

journal_title：Acta dermato-venereologica

authors： Offidani A,Cellini A,Valeri G,Giovagnoni A

更新日期：1998-11-01 00:00:00

abstract：:Atopic dermatitis is a chronic, relapsing inflammatory skin disorder characterized by local infiltration of T cells. To date, numerous reports have shown that Staphylococcus aureus may exacerbate atopic dermatitis, and superantigens produced by this organism are thought to be one of the major causative factors in atop...

journal_title：Acta dermato-venereologica

authors： Ha SJ,Lee HJ,Byun DG,Kim JW

更新日期：1998-11-01 00:00:00

abstract：:This is the first case in the literature describing naevi spili, café-au-lait spots and melanocytic naevi aggregated along-side Blaschko's lines. The pattern of melanocytic lesions in our patient is different from the congenital pigmentary syndromes and the segmental distribution of melanocytic naevi, the quadrant dis...

journal_title：Acta dermato-venereologica

authors： Langenbach N,Pfau A,Landthaler M,Stolz W

更新日期：1998-09-01 00:00:00

abstract：:Stratum corneum chymotryptic enzyme (SCCE) may be involved in desquamation, a process necessary for maintaining a normal anatomy at all sites where there is continuous turnover of cornified epithelia. Using immunohistochemistry and in situ hybridization, we have, in this work, analysed SCCE expression in the sebaceous...

journal_title：Acta dermato-venereologica

authors： Ekholm E,Sondell B,Strandén P,Brattsand M,Egelrud T

更新日期：1998-09-01 00:00:00